Puzzle Medical Devices Stock

Canadian company specializing in the development of a minimally invasive long-term hemodynamic transcatheter pump.

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About Puzzle Medical Devices Stock

Puzzle Medical is developing the ModulHeart, a modular percutaneous heart pump designed to reduce cardiac afterload and improve renal perfusion in patients with advanced heart failure who are not candidates for heart transplant or surgical mechanical circulatory support. The device’s modular design allows for hemodynamic support through multiple pumps anchored in parallel in the descending aorta. The design is expected to increase accessibility by enabling safe percutaneous implantation to support both renal and cardiac function, with low risk of bleeding, stroke, and pump thrombosis, while providing sustained symptom relief, reduced re-hospitalizations and improved overall quality of life. To date, Puzzle Medical has successfully: ○ completed its first-in-human study with all patients experiencing improvements in cardiac and kidney function (2022); ○ completed a Seed financing round (2021); ○ built a strong Key Opinion Leaders committee (2021); ○ received U.S. Food and Drug Administration (FDA) Breakthrough Device Designation (2021).

Funding History

April 2020$10.0M
February 2023$34.0M


Cofounder and CEO

Jade Doucet-Martineau

Cofounder and CSO

Gabriel Georges, MD

Cofounder and CTO

François Trudeau

Founding Advisor and CMO

Philippe Genereux, MD (Founding Advisor)

Board Member

David Prim

Board Member

Maria Berkman

Board Observer

Daniel Gottlieb

Board Member

Pascal Labrecque

Board Member

Aftab Kherani

Board Member

Duke Rohlen


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